The children were being fed by a government nutrition programme for the poor, at a remote mountain village in the north of the country.
It is thought the meal of rice and fish was prepared in a container which may have previously held rat poison.
At least three adults have also been taken ill.
The mass poisoning happened in the village of Redondo in the Cajamarca region, about 750km (470 miles) north of the capital, Lima.
The three dead were between six and 10 years old.
The food had been donated by the National Food Assistance Programme, which gives food to schools in the poorest parts of the country.
The mother of one of the children who died said they showed signs of having been poisoned.
"I think it was poison because all the kids are purple, from all parts of the school," said the mother, who was not named.
"My little boy has died. My nine-year-old boy, Miguel Angel, has died."
Peruvian health official Miguel Zumaeta said the incident "looks like it was a carbonates intoxication, which means rat poison".
Prosecutors and health ministry officials are investigating how the meal became tainted. Source
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